Asparagus racemosus (A. racemosus) belongs to family Liliaceae and commonly known as Satawar, Satamuli, Satavari which is found at low altitudes throughout India. The dried roots of the plant are used as drug. The roots are said to be tonic and diuretic and galactgogue, the drug has ulcer healing effect probably via strenthening the mucosal resistance or cytoprotection. It has also been identified as one of the drugs to control the symotoms of AIDS. A. racemosus has also been used for nervous disorder, inflammation and certain infectious disease.
- racemosus is a woody climber growing to 1-2 m in height. The leaves are like pine needles, small and uniform and flowers are white and have
small spikes.Its habitat is common at low altitudes in shade and in tropical climates throughout Asia, Australia and Africa. Out of several species of Asparagus grown in India, A. racemosus is most commonly used in indigenous medicine.
It is extensively used in male genital dysfunctions, oligospermia, spermatogenic irregularities and other male disorders such as painfull micturition . It is also explored in Ayurvedic formulations for digestive discomfort, indigestion, amoebiasis, piles and debility . In females, it is often prescribed by the doctors who face habitual abortions, weakness of the uterus, excessive bleeding during menstruation .Shatavari is also antidiarrhetic , antispasmodic, aphrodisiac , anti dysenteric, demulcent, diuretic , galactagogue, nutritive, mucilaginous, refrigerant, stomachic properties and works as a tonic for human beings.
MAJOR ACTIVE CHEMICALS:
(Singla et al 2014)
PROPERTIES AND USES:
- Antisecretory and antiulcer activity
- Antitussive effect
- Adaptogenic activity
- Anti- bacterial activity
- Anti- protozoal activity
- Gastroinstestinal effects
- Effect on uterus
- Anti- hepatotoxic activity
- Immunomodulatory activity
- Anti- oxidant activity
- Anti- depressant activity
- Aphrodisiac activity
- Enhances memory and protects against amnesia (https://www.verywellhealth.com/the-benefits-of-shatavari-88830)
- Diuretic activity
- Helps with breast milk production
- Reduces mood swings
- Helps with fertility issues
SIDE-EFFECTS OF EXCESS CONSUMPTION:
- Breast tenderness: Shatavari usually contains same properties as oestrogen, hence someone with a high oestrogen level can face breast pain and tenderness.
- Weight gain can also occur for some people
- Shatavari slightly inhibits cytochrome P450 enzymes which are prominently involved in drug metabolism.This delays the process of herb effects on the body.
As mentioned in Ayurvedic Pharmacology, 3gm to 6gm of Shatavari powder is safe for consumption
1.Asparagus racemosus is used for dyspepsia (amlapitta) and as a galactogogue. In this study, it was compared with a modern drug, metoclopramide, which is used in dyspepsia to reduce gastric emptying time. Gastric emptying half- time (GE t1/2) was studied in 8 healthy male volunteers using a cross-over design. The basal GE t1/2 in volunteers was 159.9 +/- 45.9 min (mean +/- SD) which was reduced to 101 +/- 40.8 min by Shatavari (p less than 0.001) and to 85.3 +/- 21.9 by metoclopramide (p less than 0.001). Metoclopramide and Shatavari did not differ significantly in their effects.
2. The immunoadjuvant potential of Asparagus racemosus aqueous root extract was evaluated in experimental animals immunized with diphtheria, tetanus, pertussis (DTP) vaccine in this study. Immunostimulation was evaluated using serological and hematological parameters. Oral administration of test material at 100 mg/kg per day dose for 15 days resulted significant increase (P=0.0052) in antibody titers to Bordtella pertussis as compared to untreated (control) animals. Immunized animals (treated and untreated) were challenged with B. pertussis 18323 strain and the animals were observed for 14 days. Results indicated that the treated animals showed significant increase in antibody titers as compared to untreated animals (P=0.002). Immunoprotection against intra-cerebral challenge of live B. pertussis cells was evaluated based on degree of sickness, paralysis and subsequent death. Reduced mortality accompanied with overall improved health status was observed in treated animals after intra-cerebral challenge of B. pertussis indicating development of protective immune response. This study therefore indicates applications of Shatavari as potential immunoadjuvant that also offers direct therapeutic benefits resulting in less morbidity and mortality.
3. The alcoholic Shatavari extract of rhizome was administered orally to adult pregnant female albino rats at a dose of 30 mg/100 g body weight, daily for 15 days (days 1–15 of gestation). The macroscopic findings revealed a prominence of the mammary glands, a dilated vaginal opening and a transversely situated uterine horn in the treated group of animals. The weight of the uterine horns of the treated group was found to be significantly higher (p < 0.001) but the length was shorter (p > 0.01). Microscopic examination of the treated group showed proliferation in the lumen of the duct of mammary gland. It was obliterated due to hypertrophy of ductal and glandular cells. Hyperplasia of the glandular and muscular tissue and hypertrophy of the glandular cells were observed in the genital organs. The parenchyma of the genital organs showed abundant glycogen granules with dilated blood vessels and thickening of the epithelial lining. The oviduct in the treated group showed hypertrophied muscular wall, whereas the ovary revealed no effect of the drug. These results suggest that Shatavari has an oestrogenic effect on the female mammary gland and genital organs.
4. Comparative study of the antiulcer and antisecretory activity of Asparagus racemosus (Shatawari) and Withania somnifera Dunal (Ashwagandha) root extract with a standard drug, ranitidine, in various models of gastric ulcer in rats was studied. Ulcer was induced by the indomethacin (NSAID) and swim (restraint) stress treatment. Results demonstrated that A. racemosus as well as W. somnifera methanolic extract (100 mg/kg BW/day p.o.) given orally for 15 days significantly reduced the ulcer index, volume of gastric secretion, free acidity, and total acidity. A significant increase in the total carbohydrate and total carbohydrate/protein ratio was also observed. Study also indicated an increase in antioxidant defense, that is, enzymes superoxide dismutase, catalase, and ascorbic acid, increased significantly, whereas a significant decrease in lipid peroxidation was observed. A. racemosus was more effective in reducing gastric ulcer in indomethacin‐treated gastric ulcerative rats, whereas W. somnifera was effective in stress‐induced gastric ulcer. Results obtained for both herbal drugs were compared to the standard drug ranitidine.
PRECAUTION AND WARNING:
- Shatavari should be avoided by people who have kidney or heart disorders as consuming it might prove fatal.
- Research shows that Shatavari might have slight anti-diabetic effect. If it is taken with anti-diabetic drugs, it can show additional effects thus leading to hypoglycemia.
INTERACTION WITH MEDICATIONS:
- Lithium interacts with ASPARAGUS RACEMOSUS: Asparagus racemosus might have a diuretic effect. Taking asparagus racemosus might decrease how well the body gets rid of lithium. This could increase how much lithium is in the body and result in serious side effects.
- An in vitro experiment suggests the possibility of interactions with drugs dependent on CYP3A4 metabolic pathways
All Nisarga Herbs products are tested and have no side effects.
Shatavari Root Ghan ( Asparagus racemosus) - 220 mg , Excipient - q.s.
Shatavari Root Ghan ( Asparagus racemosus) - 220 mg
Shatavari helps milk secretion in lactating mothers by enhancing proper hormonal secretion. Shatavari supports the reproductive system and helps reduce cramping and bloating normally associated with menses.