Indian turmeric is considered as one of the best turmeric in the world because of its high curcumin. Its botanical name is Curcuma longa L. and it is also known as Haridra in Sanskrit and Haldi in Hindi
Turmeric (Curcuma longa Linn) is also used as a spice and grown widely throughout Indian subcontinent. Curcumin is the main chemical compound of Turmeric and proven for its anti-inflammatory, antioxidant, antimutagenic, antidiabetic, antibacterial, hepatoprotective, expectorant and anticancerous pharmacological activities.
Haridra is used in the traditional system of medicine. It is used as an antioxidant and possesses various beneficial properties such as anti-inflammatory, anti-allergic, antiseptic, blood cleansing etc. It is widely prescribed Ayurvedic drug and is used in various diseases. The rhizome of the herb, used either fresh or dried, has a host of medicinal
benefits. Haridra is Lekhaneeya,Kushthaghna and Vishaghna. Haridra’s principal constituent, curcumin, has been extensively studied by western researchers and scientists for its antioxidant activity. Haridra is Katu and Tikta in taste. It is Ushna in quality. It is used in many forms and through many routes of administration such as nasal, oral, over the skin etc.
MAJOR CHEMICAL CONSTITUENTS:
It is composed of a number of monoterpenes and sesquiterpenes, including zingiberene, curcumene, α- and β- turmerone among others. The colouring principles (5%) are curcuminoids, 50–60% of which are a mixture of curcumin, monodesmethoxycurcumin and bisdesmethoxycurcumin.
PROPERTIES AND USES:
- anti-cancerous drug.
- widely used in cosmetology
- Neuroprotective activity
- Chemoprotective activity
- Antidermatophytic activity
- Anti- allergic activity
- Prevents drug resistance
SIDE-EFFECTS OF EXCESS CONSUMPTION:
As mentioned in Ayurvedic Pharmacology, 1gm to 3gm of powder is safe for consumption
The essential oil containing ar-turmerone, as a major component has been shown to possess anti-inflammatory effect of haridra. The free radical scavenging activity as well as inhibition of lipid peroxidation by curcumin has been reported by Kuttan et al. The down regulation of transcription factors, inhibiting COX2, LOX, inducible nitric oxide synthase, matrix metalloproteinases 9, cell adhesion molecules along with TNF-α. Curcumin inhibits TNF-α-induced AKT activation whereby levels required for NFkβ gene expression are suppressed. Curcumin suppresses the tumor angiogenesis resulting in regression in the tumor metastatic growth. Goel et al. have shown the inhibition of expression of COX2 in human colon tumor cell line (Vaidya et al.). Experimental data suggests that curcumin can act at each stage of promotion, progression, and metastasis of cancer. Haridra which has anticancer potential ,can be considered as complementary medicine for cancer treatment as well as prevention.
In this study , Hypercholesterolemia was developed in mice fed with hypercholesterolemic diet (HC) made of 1 g cholesterol, 0.2 g cholic acid and 98.8 g standard diet. Mice were fed HC diet for 15, 30, 45 and 60 days, and serum and liver cholesterol, triglycerides (TG) and total lipids (TL) were measured. Cholesterol level increased substantially at 15 days in serum and liver. It increased further at later time points upto 8 weeks. Treatment of 5% turmeric extract (TE) mixed with standard diet to hypercholesterolemic mice significantly decreased serum and hepatic cholesterol, triglycerides (TG) and total lipids (TL) levels. Feeding with 10% TE diet brought the levels comparable to those in normal untreated mice.
50 cases of conjunctivitis studies comparatively with Haridra Eye Drops and with Soframycine Eye Drops, Clinically and bacteriologically observed that Haridra Eye Drops has a definite role on conjunctivitis. Bacteriological study showed that Haridra has a role to act on E. Coli, St. Aureus Klebshella and pseudomonas organisms. 50 cases were selected mainly based on clinical finding and symptoms. Out of them, 15 were male, 12 were female and 23 were children. 25 cases were selected under the Haridra Eye Drops and 25 cases were under Soframycine 5% Eye Drops for comparative study which is non-irritant, and a broad-spectrum antibiotic to all ocular infections. In the Haridra eye drops group, E.Coli was seen in 10 cases, Staphylococcus aureus in 7 cases, Klebshella in 3 cases, Pseudomonos in 2 cases and sterile in 6 cases. E. Coli and St. aureus infection casse responded well and were completely cured in 4 days except oneeach of Klebshella and Pseudomonos cases did not respond. The results concluded that Haridra and its multifarious actions like Varnya, Kandughna and Vishaghna may be possible to reduce the clinical findings. Soshatva of Haridra quality may be the predominant feature to reduce the excessive secretions.
Curcuma longa L. (turmeric) of ginger family (Zingiberaceae) belongs to the group of oldest cultivated spice plants in the south-east Asian countries.The active substance of curcumin (diferuloylmethane) possesses multiple therapeutic properties like anti-inflammatory, antioxidant and cancer preventive properties. Even at the molecular level it has been stated that curcumin inhibits cell proliferation, metastasis creation and apoptosis. Curcumin also acts as a blocker of TNF-s, which are the principal mediators of most inflammation-related disturbances. The main cause of blocking the broadly extended pharmacological and clinical investigations of curcumin is its extremely low solubility in water and in organ fluids. This feature consequently limits its systemic bioavailability and makes use of curcumin as a therapeutic remedy (to date) difficult.
Special Precautions & Warnings:
Pregnancy and breast-feeding: During pregnancy and while breast-feeding, turmeric is likely safe when taken by mouth in amounts commonly found in food. However, turmeric is likely unsafe when taken orally in medicinal amounts during pregnancy. It might promote a menstrual period or stimulate the uterus, putting the pregnancy at risk.
Bleeding problems: Taking turmeric might slow blood clotting. This might increase the risk of bruising and bleeding in people with bleeding disorders.
Diabetes: Curcumin might decrease blood sugar in people with diabetes making blood sugar too low.
Gastroesophageal reflux disease (GERD): Turmeric can cause stomach upset in some people. It might make stomach problems such as GERD worse.
Infertility: Turmeric might lower testosterone levels and decrease sperm movement when taken by mouth by men. This might reduce fertility. Turmeric should be used cautiously by people trying to conceive.
Surgery: Turmeric might slow blood clotting. It might cause extra bleeding during and after surgery. One should stop using turmeric at least 2 weeks before a scheduled surgery.
INTERACTION WITH MEDICATIONS:
Medications changed by the liver (Cytochrome P450 3A4 (CYP3A4) substrates)Interaction.
Some medications are changed and broken down by the liver. Turmeric might decrease how quickly the liver breaks down some medications. Taking turmeric along with some medications that are broken down by the liver can increase the effects and side effects of some medications. Some medications that are changed by the liver include some calcium channel blockers (diltiazem, nicardipine, verapamil), chemotherapeutic agents (etoposide, paclitaxel, vinblastine, vincristine, vindesine), antifungals (ketoconazole, itraconazole), glucocorticoids, alfentanil (Alfenta), cisapride (Propulsid), fentanyl (Sublimaze), lidocaine (Xylocaine), losartan (Cozaar), fexofenadine (Allegra), midazolam (Versed), and others.
Anticoagulant / Antiplatelet drugs Interaction :Turmeric might slow blood clotting. Taking turmeric along with medications that also slow clotting might increase the chances of bruising and bleeding.Some medications that slow blood clotting include aspirin, clopidogrel (Plavix), diclofenac (Voltaren, Cataflam, others), ibuprofen (Advil, Motrin, others), naproxen (Anaprox, Naprosyn, others), dalteparin (Fragmin), enoxaparin (Lovenox), heparin, warfarin (Coumadin), and others.
Sulfasalazine (Azulfidine EN-Tabs)Interaction : Taking turmeric while taking sulfasalazine (Azulfidine EN-Tabs) might increase the effects and side effects of sulfasalazine (Azulfidine EN-Tabs).
Turmeric might increase the amount of tacrolimus in the body. This can increase the side effects of tacrolimus and even damage the kidneys.
All Nisarga Herbs products are tested and have no side effects.
Haridra Rhizome Ghan ( Curcuma longa) - 200 mg , Excipient - q.s.
Haridra Rhizome Ghan ( Curcuma longa) - 200 mg
Haridra contains antioxidants and supports the body with healthy response to minor inflammation.it is also traditionally used in management of neuronal disorder and modern research support this. With its reported antioxidant and regenerative properties it is vital aid in neuropathy & other neuronal disorder.